SCHEMBL15089121

SCHEMBL15089121

Nc1cccc2c1Sc1ccccc1S2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.47
ALOX5 P09917 1/20 0.43
CYP3A4 P08684 5/20 0.41
ALOX15 P16050 3/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 5/20 0.36
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAOA P21397 2/20 0.36
BCHE P06276 2/20 0.36
ACHE P22303 2/20 0.36
SLC6A2 P23975 2/20 0.36
HTR2C P28335 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2362637 0.93
SCHEMBL28405771 0.84 MEN1 (0.41) PTPN5ALOX5CYP3A4ALOX15CASP1
SCHEMBL15617266 0.78 ALDH1A1 (0.50) PTPN5ALOX5SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL3175328 0.77 NOX1 (0.38) PTPN5ALOX5CYP3A4ALOX15CASP1
SCHEMBL3078569 0.75 ALOX5 (0.66) ALOX5CYP3A4ALOX15ALDH1A1L3MBTL1
SCHEMBL30320186 0.75 ALOX5 (0.66) ALOX5CYP3A4ALOX15ALDH1A1L3MBTL1
SCHEMBL18534187 0.73 PTPN5 (0.40) PTPN5ALOX5CYP3A4ALOX15CASP1
SCHEMBL7557742 0.73 NOX1 (0.59) PTPN5CYP3A4ALOX15SMN1; SMN2ALDH1A1
SCHEMBL30823 0.72
SCHEMBL21629348 0.72 BCHE (0.56) ALOX5CYP3A4ALOX15ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133661-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2019-06-05 EP disclosed
EP-3133661-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-02-22 EP disclosed
WO-2015190718-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 2015-12-17 WO disclosed
WO-2015008940-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2015-01-22 WO disclosed
CN-102311385-B Novel 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO LTD 2015-01-14 CN disclosed
CN-102304124-B Novel 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO., LTD. (JP) 2014-10-22 CN disclosed
WO-2014129869-A1 ORGANIC FIELD EFFECT LIGHT-EMITTING DEVICE 주식회사 두산 (KR) 2014-08-28 WO disclosed
WO-2014104665-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-07-03 WO disclosed
WO-2014104664-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-07-03 WO disclosed
WO-2014092481-A1 ORGANIC COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-06-19 WO disclosed
WO-2014081133-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 WO disclosed
WO-2014081166-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2014-05-30 WO disclosed
WO-2014065498-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2014-05-01 WO disclosed
CN-102229562-B Novel 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO LTD 2013-11-13 CN disclosed
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed
CN-102311385-A Novel 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO LTD 2012-01-11 CN disclosed
CN-102304124-A Novel 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO LTD 2012-01-04 CN disclosed
CN-102229562-A Novel 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO LTD 2011-11-02 CN disclosed
CN-101263119-A Novel 1, 2-dihydroquinoline derivatives having glucocorticoid receptor binding activity SANTEN PHARMACEUTICAL CO LTD (JP) 2008-09-10 CN disclosed
CN-1036956-A New 5,6-phenylbenzene-1, the preparation method of 2-dihydro-3H-pyrrolo-[1,2-a] pyrroles-1-carboxylic acid derivative HISAMITSU PHARMACEUTICAL CO (JP) 1989-11-08 CN disclosed