Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 10/20 | 0.37 |
| ▸ | NPY1R | P25929 | 7/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 5/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390736 | 0.88 | NPY4R (0.44) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5807981 | 0.88 | NPY4R (0.44) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL4314216 | 0.88 | SIRT6 (0.52) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL160845 | 0.87 | ALOX15 (0.36) | SIRT6SIRT1NPY4RNPY1RALOX15 | |
| Hydrochloric Acid SCHEMBL11506342 | 0.87 | NPY4R (0.44) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5812127 | 0.86 | SIRT6 (0.43) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5812133 | 0.86 | SIRT6 (0.43) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL5814337 | 0.84 | SIRT6 (0.39) | SIRT6SIRT1NPY4RNPY1RSIRT5 | |
| SCHEMBL6366187 | 0.84 | NPY4R (0.34) | SIRT6SIRT1NPY4RNPY1RALOX15 | |
| SCHEMBL5814333 | 0.84 | SIRT6 (0.39) | SIRT6SIRT1NPY4RNPY1RSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111107878-A | Methods of treatment using amphetamine prodrugs | 夏尔制药公司 | 2020-05-05 | — | — | CN | disclosed |