Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 5/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406173 | 0.88 | SIRT6 (0.40) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL4314204 | 0.86 | SIRT6 (0.54) | SIRT6SIRT1TLR2PAOXCA1 | |
| SCHEMBL4314210 | 0.86 | SIRT6 (0.54) | SIRT6SIRT1TLR2PAOXCA1 | |
| SCHEMBL2390736 | 0.85 | NPY4R (0.44) | SIRT6SIRT1CA1CA2SIRT5 | |
| SCHEMBL5807981 | 0.85 | NPY4R (0.44) | SIRT6SIRT1CA1CA2SIRT5 | |
| Hydrochloric Acid SCHEMBL11506342 | 0.83 | NPY4R (0.44) | SIRT6SIRT1CA1CA2SIRT5 | |
| SCHEMBL29626768 | 0.83 | SIRT6 (0.57) | SIRT6SIRT1TLR2CA1CA2 | |
| SCHEMBL31024641 | 0.83 | SIRT6 (0.57) | SIRT6SIRT1TLR2CA1CA2 | |
| SCHEMBL5812133 | 0.82 | SIRT6 (0.43) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL5812127 | 0.82 | SIRT6 (0.43) | SIRT6SIRT1SIRT5NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570840-B1 | Topical composition comprising n-acetylamino acids | YU RUEY J (US) | 2009-04-01 | — | — | EP | disclosed |