Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830880 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL5378582 | 0.78 | ALDH1A1 (0.43) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL4891775 | 0.78 | ALDH1A1 (0.54) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL4900381 | 0.74 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL4902058 | 0.72 | CYP1A2 (0.46) | ALDH1A1GLATDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL729501 | 0.70 | ALDH1A1 (0.65) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL23431347 | 0.70 | NPSR1 (0.44) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL1351843 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL2997257 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL619267 | 0.70 | ALDH1A1 (0.53) | ALDH1A1GLATDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111206262-B | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111206262-A | Synthesis method of N-phosphino-substituted carbazole and indole derivatives | 新疆大学 | 2020-05-29 | — | — | CN | disclosed |