Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923181 | 0.90 | SLC6A3 (0.59) | TSHRLMNASLC6A3SLC6A4CA1 | |
| SCHEMBL9470734 | 0.84 | TSHR (0.71) | TSHRLMNASLC6A3SLC6A4CA1 | |
| SCHEMBL2859762 | 0.84 | TSHR (0.66) | TSHRLMNASLC6A3SLC6A4CA1 | |
| SCHEMBL29559858 | 0.83 | LMNA (0.40) | TSHRLMNASLC6A3SLC6A4CA1 | |
| SCHEMBL29109366 | 0.82 | SLC6A3 (0.64) | TSHRLMNASLC6A3SLC6A4TOP2A | |
| SCHEMBL29386013 | 0.80 | ALDH1A1 (0.55) | TSHRLMNACA1CA2CA9 | |
| Methyl Salicylate SCHEMBL5312 | 0.77 | LMNA (1.00) | TSHRLMNACA1CA2CA9 | |
| Methyl Salicylate SCHEMBL29370254 | 0.77 | LMNA (1.00) | TSHRLMNACA1CA2CA9 | |
| Methyl Salicylate SCHEMBL1872042 | 0.77 | LMNA (1.00) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL2730695 | 0.76 | LMNA (0.48) | TSHRLMNASLC6A3SLC6A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101845-B | Preparation method of eltrombopag | 苏州科伦药物研究有限公司 | 2020-05-15 | — | — | CN | disclosed |