SCHEMBL28409271

SCHEMBL28409271

C[CH]CC=CC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
FABP5 Q01469 3/20 0.45
FABP7 O15540 2/20 0.45
EPHX2 P34913 1/20 0.43
CASP3 P42574 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MAPT P10636 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15304743 0.87 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL24616691 0.84 HCAR2 (0.53) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL29396065 0.84 HCAR2 (0.53) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3403774 0.79 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL28496174 0.79 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL28090508 0.79 KMT2A (0.52) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL27794412 0.77 KMT2A (0.55) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL68446 0.77 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL19020202 0.76 KMT2A (0.43) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL27895930 0.76 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117045619-B Liposome-polymer nanoparticle loaded with melittin oncolytic peptide and adenosine A2AR receptor inhibitor, and preparation and application thereof 上海中医药大学 2024-03-29 CN disclosed
CN-117045619-A Liposome-polymer nanoparticle loaded with melittin oncolytic peptide and adenosine A2AR receptor inhibitor, and preparation and application thereof 上海中医药大学 2023-11-14 CN disclosed
CN-116964074-A Peptides that modulate VEGF IDP研发制药有限公司 2023-10-27 CN disclosed
CN-111263768-B anticancer peptides IDP研发制药有限公司 2023-10-13 CN disclosed
CN-115038712-A Nanoparticle-like delivery system 医福斯治疗有限公司 2022-09-09 CN disclosed
CN-114245800-A Melanocyte regulatory peptides IDP研发制药有限公司 2022-03-25 CN disclosed
CN-111511761-A Anticancer peptides IDP研发制药有限公司 2020-08-07 CN disclosed
CN-111263768-A Anticancer peptides IDP研发制药有限公司 2020-06-09 CN disclosed