SCHEMBL28090508

SCHEMBL28090508

O=CC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
FABP5 Q01469 3/20 0.51
FABP7 O15540 2/20 0.51
EPHX2 P34913 1/20 0.49
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CASP3 P42574 2/20 0.43
HTR2A P28223 1/20 0.41
TSHR P16473 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68446 0.85 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL24616691 0.82 HCAR2 (0.53) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL15304743 0.82 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29396065 0.82 HCAR2 (0.53) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL9081038 0.82 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL16586266 0.82 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL15981181 0.82 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL44676 0.82 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL9078154 0.82 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL30792907 0.81 KMT2A (0.48) KMT2AFABP5FABP7EPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240094120-A1 Control Of N-(Phosphonomethyl) Iminodiacetic Acid Conversion In Manufacture Of Glyphosate MONSANTO TECHNOLOGY LLC 2024-03-21 US disclosed
US-11802835-B2 Control of N-(phosphonomethyl)iminodiacetic acid conversion manufacture of glyphosate MONSANTO TECHNOLOGY LLC (US) 2023-10-31 US disclosed
CN-104684576-B PEGylated OXM variants 奥普科生物制品有限公司 2019-08-06 CN disclosed
CN-109096387-A The OXM variant of Pegylation 奥普科生物制品有限公司 2018-12-28 CN disclosed
CN-108064253-A Polymer matrices formed from carboxy-functional acrylamides 生命技术公司 2018-05-22 CN disclosed
CN-104877014-B A kind of method of purifying Te Lawan star crude products 宁夏泰瑞制药股份有限公司 2018-05-11 CN disclosed
CN-104583382-B Laundry soap bar 诺维信公司 2017-10-20 CN disclosed
CN-106994126-A Use the therapeutic scheme of various medicaments 因特利凯有限责任公司 2017-08-01 CN disclosed
CN-106924741-A Use the therapeutic scheme of various medicaments 因特利凯有限责任公司 2017-07-07 CN disclosed
CN-103703174-B Combination pharmaceutical compositions and uses thereof 因特利凯有限责任公司 2017-05-10 CN disclosed
CN-106220623-A Compounds and methods for and indication thereof for kinases regulation 普莱希科公司 2016-12-14 CN disclosed
CN-103491962-B Combinations of kinase inhibitors and uses thereof 因特利凯有限责任公司 2016-10-12 CN disclosed
CN-1328571-B The human monoclonal antibodies of anti-CTLA-4 辉瑞大药厂 2016-08-31 CN disclosed
CN-105906631-A Compounds and methods for kinase modulation, and indications therefor 普莱希科公司 2016-08-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802835-B2 Control of N-(phosphonomethyl)iminodiacetic acid conversion manufacture of glyphosate GNMT, GMNN, PTMS KMT2A 783/4885FABP5 1840/4885FABP7 3223/4885
US-20240094120-A1 Control Of N-(Phosphonomethyl) Iminodiacetic Acid Conversion In Manufacture Of Glyphosate GNMT, GMNN, PTMS KMT2A 695/4885FABP5 1896/4885FABP7 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.