Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.51 |
| ▸ | FABP7 | O15540 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616691 | 1.00 | HCAR2 (0.53) | HCAR2FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL3403774 | 0.86 | KMT2A (0.51) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL15304743 | 0.84 | KMT2A (0.49) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL28409271 | 0.84 | KMT2A (0.46) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL28090508 | 0.82 | KMT2A (0.52) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL68446 | 0.81 | KMT2A (0.51) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL27794412 | 0.81 | KMT2A (0.55) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL44677 | 0.80 | FABP5 (0.59) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL29381061 | 0.80 | FABP5 (0.59) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL29901230 | 0.80 | FABP5 (0.59) | FABP5FABP7KMT2AEPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200275-A2 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | Sitryx Therapeutics Limited (GB) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022038365-A2 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | WO | disclosed |