SCHEMBL28409276

SCHEMBL28409276

COc1ccc(OC)c(NCCO)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 4/20 0.55
KMT2A Q03164 3/20 0.54
POLB P06746 1/20 0.54
GBA1 P04062 1/20 0.54
NPSR1 Q6W5P4 1/20 0.53
GAA P10253 3/20 0.50
MAPT P10636 2/20 0.50
TP53 P04637 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 5/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12888553 0.92 RAD52 (0.56) RAD52KMT2APOLBGBA1NPSR1
SCHEMBL580933 0.89 RAD52 (0.51) RAD52KMT2APOLBGBA1NPSR1
SCHEMBL580266 0.89 RAD52 (0.51) RAD52KMT2APOLBGBA1NPSR1
SCHEMBL580480 0.89 RAD52 (0.51) RAD52KMT2APOLBGBA1NPSR1
SCHEMBL580355 0.89 RAD52 (0.51) RAD52KMT2APOLBGBA1NPSR1
SCHEMBL2434485 0.86 ALDH1A1 (0.57) GBA1GAAMAPTTP53L3MBTL1
SCHEMBL5663443 0.84 KMT2A (0.51) KMT2ANPSR1GAAMAPTTP53
SCHEMBL14141593 0.83 LMNA (0.55) KMT2ANPSR1GAAMAPTTP53
SCHEMBL27957659 0.83 KMT2A (0.50) KMT2ANPSR1GAAMAPTTP53
SCHEMBL5162466 0.83 POLB (0.44) RAD52KMT2APOLBGBA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462403-A Preparation method of 2- ((2, 5-dimethoxy phenyl) amino) ethane-1-alcohol 江南大学 2025-02-18 CN claimed
CN-122094941-A Novel azido formation of 6-hydroxy-benzomorpholine (3, 4-dihydro-2H-1, 4-benzoxazin-6-ol) 2026-05-26 CN disclosed
CN-122094942-A Novel azide condensation of 6-hydroxybenzomorpholine (3, 4-dihydro-2H-1, 4-benzoxazin-6-ol) 2026-05-26 CN disclosed
WO-2025099127-A1 NEW TELESCOPING SYNTHESES OF 6-HYDROXY-BENZOMORPHOLINE (3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-OL) WELLA GERMANY GMBH (DE) 2025-05-15 WO disclosed
WO-2025099125-A1 NEW TELESCOPING SYNTHESES OF 6-HYDROXY-BENZOMORPHOLINE (3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-OL) WELLA GERMANY GMBH (DE) 2025-05-15 WO disclosed
WO-2025099111-A1 NEW TELESCOPING SYNTHESES OF 6-HYDROXY-BENZOMORPHOLINE (3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-OL) WELLA GERMANY GMBH (DE) 2025-05-15 WO disclosed
CN-119462403-A Preparation method of 2- ((2, 5-dimethoxy phenyl) amino) ethane-1-alcohol 江南大学 2025-02-18 CN disclosed
CN-111170958-B Preparation method of hydroxybenzomorph 浙江鼎龙科技股份有限公司 2021-08-10 CN disclosed
CN-111170958-A Preparation method of hydroxybenzomorph 浙江鼎龙科技有限公司 2020-05-19 CN disclosed