Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BCL6 | P41182 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22333905 | 0.90 | APP (0.43) | POLBALDH1A1BCL6TUBB4ATUBB | |
| SCHEMBL8348474 | 0.86 | KDM4E (0.51) | POLBALDH1A1BCL6TNFKDM4E | |
| SCHEMBL9125673 | 0.85 | ALDH1A1 (0.50) | POLBALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL3878469 | 0.85 | BACE1 (0.47) | POLBALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11144337 | 0.85 | CASP3 (0.55) | POLBALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL11822323 | 0.83 | MAPT (0.58) | POLBALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL12000685 | 0.83 | ALDH1A1 (0.51) | POLBALDH1A1BCL6TUBB4ATUBB | |
| SCHEMBL3859668 | 0.83 | TUBB4A (0.57) | ALDH1A1BCL6TUBB4ATUBBTUBA3C | |
| SCHEMBL28409276 | 0.83 | RAD52 (0.55) | POLBALDH1A1KDM4EGBA1L3MBTL1 | |
| SCHEMBL3904069 | 0.83 | KDM4E (0.46) | POLBALDH1A1TNFKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663814-A1 | PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1995-07-26 | — | — | EP | claimed |
| WO-1993010744-A2 | PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1993-06-10 | — | — | WO | claimed |
| US-5180396-A | Process for dyeing keratinous fibres with oxidation dyes combined with indole derivatives and dyeing composition employed | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| US-5180397-A | Hair dyes | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| US-4985955-A | INTENSE COLORATIONS IN RELATIVELY SHORT TIMES | L'OREAL (FR) | 1991-01-22 | — | — | US | claimed |
| EP-1758545-A1 | 4,5,6-SUBSTITUTED M-PHENYLENE DIAMINE COUPLING COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006050768-A1 | NOVEL M-PHENYLENEDIAMINE COUPLER COMPOUNDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-05-18 | — | — | WO | disclosed |
| EP-1647266-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-04-19 | — | — | EP | disclosed |
| US-20060016024-A1 | Novel coupling components | PARALLEL WIRELESS, INC. | 2006-01-26 | — | — | US | disclosed |
| WO-2005117818-A1 | 4,5,6-SUBSTITUTED M-PHENYLENE DIAMINE COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-15 | — | — | WO | disclosed |
| EP-1583511-B1 | NOVEL COUPLING COMPONENTS | HENKEL KGAA (DE) | 2005-11-09 | — | — | EP | disclosed |
| EP-0640334-B1 | Hair coloring composition | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0399746-B1 | USE OF CHLORITES AS OXIDANTS IN HAIR COLORING | Bristol-Myers Squibb Company (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5180396-A | Process for dyeing keratinous fibres with oxidation dyes combined with indole derivatives and dyeing composition employed | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |
| US-5180397-A | Hair dyes | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |
| EP-0507448-A2 | Oxidative hair dyeing process with catalytic pretreatment | Bristol-Myers Squibb Company (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5100436-A | Transition metal complex of 2,2*-dipyridine or 1,10-phenanthroline deposited on hair, reduced time for coloring | CLAIROL INCORPORATED (US) | 1992-03-31 | — | — | US | disclosed |
| US-5032138-A | Chlorites as oxidants in hair coloring | CLAIROL INCORPORATED (US) | 1991-07-16 | — | — | US | disclosed |
| US-4985955-A | INTENSE COLORATIONS IN RELATIVELY SHORT TIMES | L'OREAL (FR) | 1991-01-22 | — | — | US | disclosed |
| EP-0399746-A1 | Use of chlorites as oxidants in hair coloring | Bristol-Myers Squibb Company (US) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060016024-A1 | Novel coupling components | KRT18, H1-4, H1-3 | POLB 1808/4885ALDH1A1 1969/4885BCL6 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.