SCHEMBL28409684

SCHEMBL28409684

Cc1cccc(Cl)c1C=O.Clc1cccs1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
LCK P06239 2/20 0.36
RORC P51449 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35
MAPT P10636 5/20 0.35
GAA P10253 3/20 0.35
NPC1 O15118 1/20 0.35
KDM4E B2RXH2 2/20 0.34
POLB P06746 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
RAB9A P51151 2/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
ERN1 O75460 1/20 0.33
RECQL P46063 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910073 0.84 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ATDP1RORC
SCHEMBL27881137 0.72
Formic Acid SCHEMBL5347004 0.70
SCHEMBL66979 0.70 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ATDP1NPSR1
SCHEMBL96214 0.70 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATDP1NPSR1
SCHEMBL7073829 0.70
SCHEMBL29054 0.70
SCHEMBL384643 0.68 F2 (0.39) ALDH1A1MEN1KMT2ATDP1MAPT
SCHEMBL28806185 0.68 ALDH1A1 (0.94) ALDH1A1MEN1KMT2ATDP1NPSR1
Cyanide SCHEMBL27917051 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111253383-A Synthetic method of rivaroxaban 南京国星生物技术研究院有限公司 2020-06-09 CN disclosed