SCHEMBL96214

SCHEMBL96214

O=Cc1c(Cl)cccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 2/20 1.00
HSP90AA1 P07900 1/20 0.46
CYP1A2 P05177 3/20 0.43
CYP2A6 P11509 2/20 0.43
LMNA P02545 3/20 0.42
TSHR P16473 3/20 0.42
SLC22A1 O15245 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
MAOA P21397 1/20 0.40
DRD1 P21728 1/20 0.40
TBXA2R P21731 1/20 0.40
SLC6A2 P23975 1/20 0.40
ADRA1D P25100 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28806185 0.97 ALDH1A1 (0.94) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL3784795 0.85 TDP1 (0.73) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL23498153 0.84 ALDH1A1 (0.71) ALDH1A1KMT2ATDP1MEN1HSP90AA1
Diethylamine SCHEMBL11627853 0.84 ALDH1A1 (0.71) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL31257925 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL1571095 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ATDP1MEN1HSP90AA1
Water SCHEMBL28568606 0.83 TDP1 (0.70) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL910073 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL611923 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ATDP1MEN1HSP90AA1
SCHEMBL953519 0.83 ALDH1A1 (0.70) ALDH1A1KMT2ATDP1MEN1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3034 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010730-A Preparation method of key intermediate of Lutrepah 重庆常捷医药有限公司 2026-05-12 CN claimed
CN-119707667-A Preparation method of 2-acetyl-6-hydroxybenzoic acid 江苏致容生物研发有限公司 2025-03-28 CN claimed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-119462673-A Preparation method of macromolecular heterocyclic compound 康龙化成(绍兴)药业有限公司 2025-02-18 CN claimed
CN-118955912-A Phosphazene polymer microsphere, preparation method and application 山东泰星新材料股份有限公司 2024-11-15 CN claimed
CN-118715212-A Preparation of N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof FMC公司 2024-09-27 CN claimed
CN-116139934-B Efficient catalyst for catalyzing hydroboration reaction of aldehyde and ketone and application 北京理工大学 2024-08-30 CN claimed
CN-118496215-A Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-08-16 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
EP-0049604-A1 CNS stimulants AMERICAN HOME PRODUCTS CORPORATION (US) 1982-04-14 EP claimed
US-4322429-A Isoxazolylbenzamides as insecticides ELI LILLY AND COMPANY (US) 1982-03-30 US claimed
EP-0048162-A1 Isoxazolylbenzamides ELI LILLY AND COMPANY (US) 1982-03-24 EP claimed
US-4251331-A USING AN A-AMINO ALIPHATIC CARBOXYLIC ACID BRIGHTENING AGENT, AND A NONIONIC SURFACTANT; AN AQUEOUS ACID BATH COLUMBIA CHEMICAL CORPORATION (US) 1981-02-17 US claimed
US-4235807-A Synthesis of 2,6-disubstituted benzonitriles THOMPSON-HAYWARD CHEMICAL COMPANY (US) 1980-11-25 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-4136122-A SEPARATION OF 2,6-DICHLOROBENZALDEHYDE FROM ISOMERIC MIXTURES HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-01-23 US claimed
US-4049510-A AMINE POLYMER AND A PROPYLENE OXIDE-ETHYLENE OXIDE BLOCK COPOLYMER ION COLUMBIA CHEMICAL CORPORATION (US) 1977-09-20 US claimed
US-4007098-A USING THE REACTION PRODUCT OF A LINEAR AMINE POLYMER AND AN EPIHALOHYDRIN COLUMBIA CHEMICAL CORPORATION (US) 1977-02-08 US claimed
US-3988219-A Baths and additives for the electrodeposition of bright zinc COLUMBIA CHEMICAL CORPORATION (US) 1976-10-26 US claimed