Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409684 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL96214 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL66979 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL28641344 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| Hydrogen Sulfide SCHEMBL28185526 | 0.80 | ALDH1A1 (0.94) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL28806185 | 0.80 | ALDH1A1 (0.94) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| Methylene Chloride SCHEMBL27759956 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL14127122 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL11336391 | 0.78 | KMT2A (0.47) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL11336396 | 0.78 | KMT2A (0.47) | ALDH1A1KMT2AMEN1TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110606855-B | Polysubstituted benzothienoisoquinoline, derivative and synthesis method thereof | 湘潭大学 | 2022-03-18 | — | — | CN | claimed |
| CN-116710439-B | Substituted pyrazolopiperidine carboxylic acids | BAYER AG (DE) | 2026-05-26 | — | — | CN | disclosed |
| US-20250115608-A1 | HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | ARDELYX, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-12209088-B2 | Hormone receptor modulators for treating metabolic conditions and disorders | ARDELYX, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-118787643-A | Substituted pyrazolopiperidine carboxylic acids | 拜耳公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118791463-A | Substituted pyrazolopiperidine carboxylic acids | 拜耳公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-114981257-B | Substituted pyrazolopiperidine carboxylic acids | 拜耳公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113683499-B | Method for preparing Du Weili siberian intermediate | 上海皓鸿生物医药科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116854681-A | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-4423241-A | Herbicidal composition | UNION CARBIDE CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0077854-A1 | Herbicidal halogenated aromatic aminooxyacetic acid compounds and methods of use | UNION CARBIDE CORPORATION (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4271164-A | HYPOTENSIVE AGENTS | WARNER-LAMBERT COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| EP-0018151-A1 | 6-Substituted-arylpyrido(2,3-d)pyrimidin-7-amines, derivatives and salts thereof, pharmaceutical compositions containing any of the foregoing, and processes for producing any of the foregoing | WARNER-LAMBERT COMPANY (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4024274-A | Benzylamine derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209088-B2 | Hormone receptor modulators for treating metabolic conditions and disorders | NR1H4, FXR1, GLP1R | ALDH1A1 2057/4885KMT2A 2388/4885MEN1 343/4885 |
| US-20250115608-A1 | HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | NR1H4, FXR1, GLP1R | ALDH1A1 2057/4885KMT2A 2388/4885MEN1 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.