Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.69 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.57 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.51 |
| ▸ | TUBB | P07437 | 2/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416680 | 0.91 | GLO1 (0.67) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28891601 | 0.88 | GLO1 (0.56) | STAT3GLO1SLC40A1ACLYMEN1 | |
| SCHEMBL28418719 | 0.86 | CKS1B (0.65) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28410557 | 0.85 | TUBB4A (0.69) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28410436 | 0.85 | GLO1 (0.60) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28418717 | 0.83 | STAT3 (0.72) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28422418 | 0.83 | PTGES2 (0.56) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28422416 | 0.82 | MEN1 (0.63) | GLO1SLC40A1MEN1KMT2ATDP1 | |
| SCHEMBL28410070 | 0.82 | KMT2A (0.57) | STAT3GLO1SLC40A1MEN1KMT2A | |
| SCHEMBL28415451 | 0.82 | MEN1 (0.62) | STAT3GLO1SLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320575-B | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111320575-A | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2020-06-23 | — | — | CN | disclosed |