Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 3/20 | 0.65 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.65 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.64 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.57 |
| ▸ | TUBB | P07437 | 2/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416680 | 0.95 | GLO1 (0.67) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28410557 | 0.89 | TUBB4A (0.69) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28410436 | 0.89 | GLO1 (0.60) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28412972 | 0.89 | GLO1 (0.63) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28422418 | 0.89 | PTGES2 (0.56) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28422416 | 0.89 | MEN1 (0.63) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28891064 | 0.86 | SLC40A1 (0.60) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28410068 | 0.86 | STAT3 (0.69) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28418722 | 0.86 | GLO1 (0.60) | CKS1BSKP2SLC40A1GLO1POLB | |
| SCHEMBL28410070 | 0.86 | KMT2A (0.57) | CKS1BSKP2SLC40A1GLO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320575-B | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111320575-A | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2020-06-23 | — | — | CN | disclosed |