Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31252137 | 0.95 | ATM (0.43) | GAAKMT2ANPSR1ALDH1A1USP2 | |
| SCHEMBL10437828 | 0.93 | USP2 (0.43) | GAANPSR1ALDH1A1USP2TSHR | |
| SCHEMBL28606626 | 0.82 | KDM4E (0.36) | GAAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL26915222 | 0.81 | ELANE (0.43) | GAARECQLMEN1KMT2AALDH1A1 | |
| SCHEMBL16351364 | 0.81 | ALDH1A1 (0.43) | GAAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL13596168 | 0.80 | MEN1 (0.46) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL1501165 | 0.80 | MEN1 (0.46) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL2551073 | 0.80 | MEN1 (0.46) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL29239698 | 0.80 | ALDH1A1 (0.46) | GAAKMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL27015413 | 0.79 | ALDH1A1 (0.40) | GAANPSR1ALDH1A1TSHRELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914271-A | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2020-03-24 | — | — | CN | disclosed |