Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437828 | 0.96 | USP2 (0.43) | ATMUSP2TSHRNPSR1ALDH1A1 | |
| SCHEMBL28410516 | 0.95 | GAA (0.42) | ATMUSP2TSHRNPSR1ALDH1A1 | |
| SCHEMBL17040981 | 0.79 | ALDH1A1 (0.41) | ATMTSHRNPSR1ALDH1A1KMT2A | |
| SCHEMBL16351364 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL29239698 | 0.78 | ALDH1A1 (0.46) | TSHRALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28606626 | 0.77 | KDM4E (0.36) | TSHRALDH1A1MAPTKMT2AHTT | |
| SCHEMBL38654078 | 0.76 | GAA (0.39) | TSHRNPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL28388395 | 0.76 | CYP4F2 (0.41) | HTTSMN1; SMN2 | |
| SCHEMBL22070851 | 0.76 | HSD11B1 (0.36) | ATMUSP2NPSR1ALDH1A1MAPT | |
| SCHEMBL26915222 | 0.76 | ELANE (0.43) | ATMALDH1A1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720072-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249299-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-12-05 | — | — | WO | disclosed |