Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351364 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28410516 | 0.82 | GAA (0.42) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9845210 | 0.82 | ELANE (0.39) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL31033327 | 0.81 | THRB (0.43) | SMN1; SMN2MAPTALDH1A1TSHRHTT | |
| SCHEMBL2904671 | 0.80 | ALDH1A1 (0.43) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29864513 | 0.79 | ELANE (0.37) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL26566724 | 0.79 | CYP3A4 (0.37) | SMN1; SMN2MAPTPIN1HTTCYP3A4 | |
| SCHEMBL25770231 | 0.78 | POLB (0.45) | KDM4ESMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL38654078 | 0.77 | GAA (0.39) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL31252137 | 0.77 | ATM (0.43) | KDM4EKMT2ASMN1; SMN2MAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272302-A | Antibiotic compounds, process for their manufacture, pharmaceutical compositions containing them and their use | 德彪药业国际股份公司 | 2021-08-17 | — | — | CN | disclosed |