Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331070 | 0.91 | MAOB (0.42) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL942085 | 0.90 | DRD2 (0.46) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL9885083 | 0.90 | DRD2 (0.46) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL942084 | 0.90 | DRD2 (0.46) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL965092 | 0.85 | DRD2 (0.44) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL6642035 | 0.85 | DRD2 (0.44) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL25318818 | 0.85 | DRD2 (0.44) | DRD2DRD3MAOBKDM1AHPGD | |
| SCHEMBL27091219 | 0.84 | MAOB (0.41) | DRD2MAOBKDM1AKMT2AMAOA | |
| SCHEMBL25322036 | 0.83 | MAOB (0.43) | MAOBKDM1AKMT2AACACBMAOA | |
| SCHEMBL29013154 | 0.83 | GPR119 (0.43) | KMT2AACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |
| CN-111269199-B | Preparation method of cariprazine | 浙江京新药业股份有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-111269211-B | Preparation method of benzothiophene derivative | 浙江京新药业股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-111100112-B | Benzothiophene derivative and process for producing the same | 浙江京新药业股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-111269199-A | Preparation method of cariprazine | 浙江京新药业股份有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-111269211-A | Preparation method of benzothiophene derivative | 浙江京新药业股份有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-111100112-A | Benzothiophene derivative and process for producing the same | 浙江京新药业股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-111100110-A | Process for preparing 7-piperazinylbenzothiophenes or salts thereof | 浙江京新药业股份有限公司 | 2020-05-05 | — | — | CN | disclosed |