SCHEMBL28412397

SCHEMBL28412397

CC1(C(=O)O)CCC=CC(O)CC1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.45
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24004674 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL27044680 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL28412398 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL31324041 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL23897414 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL28658467 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL24004769 1.00 FFAR3 (0.45) FFAR3CYP19A1
SCHEMBL25963527 0.86 CYP19A1 (0.32) CYP19A1
SCHEMBL26103315 0.79 MME (0.35)
SCHEMBL25963073 0.78 FFAR3 (0.41) FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12611461-B2 Bioorthogonal compositions TAMBO, INC. (US) 2026-04-28 US disclosed
EP-4704904-A1 TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD Tambo, Inc. (US) 2026-03-11 EP disclosed
US-20250255970-A1 BIOORTHOGONAL COMPOSITIONS TAMBO INC (US) 2025-08-14 US disclosed
US-12296017-B2 Bioorthogonal compositions TAMBO, INC. (US) 2025-05-13 US disclosed
WO-2024229427-A1 TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD TAMBO, INC. (US) 2024-11-07 WO disclosed
EP-4458896-A2 BIOORTHOGONAL COMPOSITIONS Tambo, Inc. (US) 2024-11-06 EP disclosed
CN-111093708-B Bioorthogonal compositions 坦伯公司 2024-10-29 CN disclosed
EP-3606559-B1 BIOORTHOGONAL COMPOSITIONS TAMBO INC (US) 2024-06-05 EP disclosed
US-20220259254-A1 TRANS-CYCLOOCTENE BIOORTHOGONAL AGENTS AND USES IN CANCER AND IMMUNOTHERAPY TAMBO, INC. 2022-08-18 US disclosed
US-20220168426-A1 BIOORTHOGONAL COMPOSITIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-06-02 US disclosed
EP-3993834-A1 TRANS-CYCLOOCTENE BIOORTHOGONAL AGENTS AND USES IN CANCER AND IMMUNOTHERAPY Tambo, Inc. (US) 2022-05-11 EP disclosed
CN-114340680-A Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy 坦博公司 2022-04-12 CN disclosed
US-11253600-B2 Bioorthogonal compositions TAMBO, INC. (US) 2022-02-22 US disclosed
CN-111093708-A Bioorthogonal compositions 坦伯公司 2020-05-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259254-A1 TRANS-CYCLOOCTENE BIOORTHOGONAL AGENTS AND USES IN CANCER AND IMMUNOTHERAPY TIE1, CD74, MERTK FFAR3 3476/4885CYP19A1 1097/4885
US-12296017-B2 Bioorthogonal compositions TIE1, BBOX1, ST14 FFAR3 3156/4885CYP19A1 916/4885
US-20220168426-A1 BIOORTHOGONAL COMPOSITIONS TIE1, BBOX1, ST14 FFAR3 3156/4885CYP19A1 916/4885
US-12611461-B2 Bioorthogonal compositions ACVRL1, FCGR2A, CHIT1 FFAR3 3726/4885CYP19A1 2661/4885
US-11253600-B2 Bioorthogonal compositions TIE1, BBOX1, ST14 FFAR3 3156/4885CYP19A1 916/4885
US-20250255970-A1 BIOORTHOGONAL COMPOSITIONS TIE1, BBOX1, ST14 FFAR3 3156/4885CYP19A1 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.