Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.43 |
| ▸ | TUBB | P07437 | 4/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642141 | 0.77 | CYP11B1 (0.41) | ACHEL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11124049 | 0.75 | CA9 (0.42) | L3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18497036 | 0.75 | CYP11B1 (0.40) | LMNAKMT2AL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL3309703 | 0.74 | CYP11B1 (0.40) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16339494 | 0.74 | CYP11B1 (0.57) | KMT2AL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL24984552 | 0.73 | CYP11B1 (0.39) | L3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11123134 | 0.72 | LMNA (0.47) | LMNATDP1POLBL3MBTL1CYP19A1 | |
| SCHEMBL8920608 | 0.72 | CA12 (0.47) | LMNATDP1POLBKMT2AL3MBTL1 | |
| SCHEMBL98343 | 0.71 | HTR5A (0.50) | KMT2AMEN1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11120453 | 0.71 | HTT (0.42) | ATMACHELMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170918-B | Method for synthesizing gamma-lactam and delta-lactam through C-H amine | 山东大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-111170918-A | Method for synthesizing gamma-lactam and delta-lactam through C-H amine | 山东大学 | 2020-05-19 | — | — | CN | disclosed |