Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.74 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.77 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11269703 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| Bromide SCHEMBL10730576 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| Bromide SCHEMBL7032019 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| Bromide SCHEMBL5549665 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL339686 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890583 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890107 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL8773435 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2887852 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2882451 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253507-B | Method for preparing hydrogenated polymer material by hydrazine hydrate heterogeneous solution reaction | 青岛科技大学 | 2023-03-24 | — | — | CN | claimed |
| CN-111253507-A | Method for preparing hydrogenated polymer material by hydrazine hydrate heterogeneous solution reaction | 青岛科技大学 | 2020-06-09 | — | — | CN | claimed |
| CN-111253507-B | Method for preparing hydrogenated polymer material by hydrazine hydrate heterogeneous solution reaction | 青岛科技大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-111253507-A | Method for preparing hydrogenated polymer material by hydrazine hydrate heterogeneous solution reaction | 青岛科技大学 | 2020-06-09 | — | — | CN | disclosed |