Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889761 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2748121 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL339686 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2882451 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890107 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890583 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL1692071 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890680 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2887852 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL253468 | 1.00 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562639-B1 | Shampoo compositions and suspending agent therefor | CURTIS HELENE IND INC (US) | 1997-10-29 | — | — | EP | claimed |
| EP-0562637-B1 | Opacifier for water-based compositions | CURTIS HELENE IND INC (US) | 1997-05-28 | — | — | EP | claimed |
| US-5463094-A | Solvent free quaternization of tertiary amines with dimethylsulfate | HOECHST CELANESE CORPORATION (US) | 1995-10-31 | — | — | US | claimed |
| EP-0562639-A1 | Shampoo compositions and suspending agent therefor | HELENE CURTIS, INC. (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0562637-A1 | Opacifier for water-based compositions | HELENE CURTIS, INC. (US) | 1993-09-29 | — | — | EP | claimed |
| EP-2776390-B1 | NOVEL METHOD TO MANUFACTURE SURFACE ACTIVE COMPOUNDS SUCH AS SULFATE BETAINE | RHODIA OPERATIONS (FR) | 2016-07-13 | — | — | EP | disclosed |
| US-9187414-B2 | Method to manufacture surface active compounds such as sulfate betaine | RHODIA OPERATIONS (FR) | 2015-11-17 | — | — | US | disclosed |
| US-20140343312-A1 | Novel method to manufacture surface active compounds such as sulfate betaine | RHODIA OPERATIONS a corporation | 2014-11-20 | — | — | US | disclosed |
| EP-2776390-A1 | NOVEL METHOD TO MANUFACTURE SURFACE ACTIVE COMPOUNDS SUCH AS SULFATE BETAINE | Rhodia Operations (FR) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013067915-A1 | NOVEL METHOD TO MANUFACTURE SURFACE ACTIVE COMPOUNDS SUCH AS SULFATE BETAINE | RHODIA OPERATIONS (FR) | 2013-05-16 | — | — | WO | disclosed |
| EP-0562639-B1 | Shampoo compositions and suspending agent therefor | CURTIS HELENE IND INC (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5665267-A | Shampoo compositions and suspending agent therefor | HELENE CURTIS, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5587154-A | COMPRISING A FATTY-TERT, SECONDARY- OR PRIMARY-AMINE AND AN ACID AS DISPERSANTS | HELENE CURTIS, INC. (US) | 1996-12-24 | — | — | US | disclosed |
| US-5562898-A | Opacifier for water-based compositions | HELENE CURTIS, INC. (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0684223-A1 | Solvent free quaternization of tertiary amines with dimethylsulfate | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5463094-A | Solvent free quaternization of tertiary amines with dimethylsulfate | HOECHST CELANESE CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| US-5393519-A | Homogeneous; containing a conditioner | HELENE CURTIS, INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5384114-A | Long chain amine salt | HELENE CURTIS, INC. (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0562639-A1 | Shampoo compositions and suspending agent therefor | HELENE CURTIS, INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0562637-A1 | Opacifier for water-based compositions | HELENE CURTIS, INC. (US) | 1993-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343312-A1 | Novel method to manufacture surface active compounds such as sulfate betaine | SGMS2, SGMS1, SMS | MAOA 1370/4885CHRM2 1768/4885SIGMAR1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.