Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.74 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.77 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28412992 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| Bromide SCHEMBL11269703 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| Bromide SCHEMBL10730576 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| Bromide SCHEMBL5549665 | 1.00 | MAOA (0.77) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL339686 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890583 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2890107 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL8773435 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2887852 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL2882451 | 0.98 | MAOA (0.80) | MAOACHRM2SIGMAR1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117981751-A | Composite disinfectant and preparation method thereof | 中国人民解放军疾病预防控制中心 | 2024-05-07 | — | — | CN | claimed |
| CN-116949533-A | Aluminum alloy anodic oxidation anti-film crack pre-sealing agent and sealing process thereof | 深圳万佳原精化科技股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-111253507-B | Method for preparing hydrogenated polymer material by hydrazine hydrate heterogeneous solution reaction | 青岛科技大学 | 2023-03-24 | — | — | CN | claimed |
| CN-114763319-A | Method for co-producing valproamide and sodium valproate | 湖南大学 | 2022-07-19 | — | — | CN | claimed |
| CN-111548073-B | Anti-shrinkage prefabricated part concrete and preparation method and application thereof | 广州市建筑科学研究院有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113461725-A | Long-chain siloxane glyceride, blended calcium carbonate powder activator and preparation method | 浙江钦堂钙业有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-112494348-A | Antibacterial no-clean hand sanitizer and preparation method and application thereof | 上海和黄白猫有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-110205619-B | Chemical cleaning pre-filming process for industrial galvanizing equipment | 河南省科学院能源研究所有限公司 | 2020-12-04 | — | — | CN | claimed |
| CN-111548073-A | Anti-shrinkage prefabricated part concrete and preparation method and application thereof | 广州市建筑科学研究院有限公司 | 2020-08-18 | — | — | CN | claimed |
| CN-111253507-A | Method for preparing hydrogenated polymer material by hydrazine hydrate heterogeneous solution reaction | 青岛科技大学 | 2020-06-09 | — | — | CN | claimed |
| CN-110205619-A | A kind of pre- membrane process of industry galvanizing equipment chemical cleaning | 河南省科学院能源研究所有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-110028672-A | A kind of sulfur-bearing, nitrogen, oxygen atom comb shape polysulfide ether compound and its preparation method and use | 烟台大学 | 2019-07-19 | — | — | CN | claimed |
| CN-105565556-B | The fracturing outlet liquid and its application that the processing method of fracturing outlet liquid and processing obtain | 中国石油化工股份有限公司 | 2019-01-08 | — | — | CN | claimed |
| CN-105766984-A | Biocide of marine organisms | 广东省石油化工研究院 | 2016-07-20 | — | — | CN | claimed |
| CN-101601409-A | Sterilization and alga-killing remover for circulating water | LANZHOU HUAXING HIGH TECH DEV (CN) | 2009-12-16 | — | — | CN | claimed |
| CN-117981751-A | Composite disinfectant and preparation method thereof | 中国人民解放军疾病预防控制中心 | 2024-05-07 | — | — | CN | disclosed |
| CN-113967411-B | Phosphate-free reverse osmosis membrane scale inhibitor for scale inhibition of calcium ions, magnesium ions, copper ions and barium ions and preparation method thereof | 威海君创环保科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| EP-0109223-B1 | ELECTROLYTE FOR ZINC-BROMINE STORAGE BATTERIES | KABUSHIKI KAISHA MEIDENSHA MEIDENSHA ELECTRIC MFG. CO., LTD. (JP) | 1987-07-22 | — | — | EP | disclosed |
| EP-0109223-A1 | Electrolyte for zinc-bromine storage batteries | KABUSHIKI KAISHA MEIDENSHA MEIDENSHA ELECTRIC MFG. CO., LTD. (JP) | 1984-05-23 | — | — | EP | disclosed |
| US-4331447-A | ADDING AN OIL FRACTION AS A BINDER TO AN AQUEOUS SLURRY | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-25 | — | — | US | disclosed |