Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409735 | 0.83 | POLB (0.32) | PIN1POLBCASP6 | |
| SCHEMBL30961423 | 0.77 | KDM4E (0.36) | PIN1 | |
| SCHEMBL30961284 | 0.75 | MYC (0.39) | — | |
| SCHEMBL27145902 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL28809315 | 0.73 | — | — | |
| SCHEMBL1442195 | 0.73 | TYRO3 (0.32) | POLBCASP6 | |
| SCHEMBL6203110 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL6219173 | 0.71 | AURKA (0.34) | — | |
| SCHEMBL6203090 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL6204668 | 0.71 | PDXK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303125-A | Methoxy-substituted indole-pyrimidine compound and preparation method thereof | 天津法莫西医药科技有限公司 | 2020-06-19 | — | — | CN | disclosed |