Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964360 | 0.84 | HPGD (0.56) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL14084700 | 0.83 | HPGD (0.61) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL5072014 | 0.77 | HPGD (0.55) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL29807129 | 0.74 | GAA (0.50) | KDM4ESMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL933745 | 0.74 | GAA (0.50) | KDM4ESMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL6534180 | 0.73 | HPGD (1.00) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL30935678 | 0.73 | HPGD (1.00) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL29804862 | 0.72 | RAB9A (0.71) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL3986163 | 0.72 | RAB9A (0.71) | HPGDRAB9ACTSVCTSLKDM4E | |
| SCHEMBL5584214 | 0.71 | GPR84 (0.42) | HPGDKDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586457-B | indole carbocycle dearomatization synthesis method based on nitrogen atom α hydrogen migration strategy | 青岛农业大学 | 2020-05-19 | — | — | CN | disclosed |