Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384362 | 0.97 | EGFR (0.45) | EGFRMAPK3ERBB2ERBB3ERBB4 | |
| SCHEMBL28412163 | 0.93 | EGFR (0.42) | EGFR | |
| SCHEMBL28422007 | 0.93 | EGFR (0.41) | EGFR | |
| SCHEMBL28384393 | 0.92 | SLC6A3 (0.45) | — | |
| SCHEMBL28388785 | 0.91 | EGFR (0.43) | EGFR | |
| SCHEMBL28394117 | 0.90 | EGFR (0.43) | EGFR | |
| SCHEMBL28387179 | 0.87 | EGFR (0.49) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL28418732 | 0.87 | EGFR (0.41) | EGFR | |
| SCHEMBL28384151 | 0.86 | ALK (0.47) | EGFR | |
| SCHEMBL28386146 | 0.86 | SLC6A3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |