Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28394117 | 0.97 | EGFR (0.43) | EGFRJAK3 | |
| SCHEMBL28412163 | 0.93 | EGFR (0.42) | EGFRJAK3 | |
| SCHEMBL28414763 | 0.93 | EGFR (0.43) | EGFR | |
| SCHEMBL28388000 | 0.92 | — | — | |
| SCHEMBL28388785 | 0.91 | EGFR (0.43) | EGFRJAK3 | |
| SCHEMBL28384362 | 0.90 | EGFR (0.45) | EGFRJAK3 | |
| SCHEMBL28394013 | 0.87 | EGFR (0.39) | EGFR | |
| SCHEMBL28383183 | 0.87 | EGFR (0.47) | EGFRJAK3 | |
| SCHEMBL28416830 | 0.87 | EGFR (0.39) | EGFR | |
| SCHEMBL28386146 | 0.86 | SLC6A3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |