Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448050 | 0.87 | LMNA (0.43) | HTR2CHTR2ALMNAHSD17B10CHRNA7 | |
| SCHEMBL28740986 | 0.87 | LMNA (0.43) | HTR2CHTR2ALMNAHSD17B10CHRNA7 | |
| SCHEMBL2817474 | 0.84 | HTR2C (0.55) | HTR2CHTR2BOPRM1ADRB2HTR1A | |
| SCHEMBL12086613 | 0.79 | HTR1A (0.44) | HTR2CHTR2BOPRM1ADRB2HTR1A | |
| SCHEMBL2817660 | 0.78 | ALDH1A1 (0.47) | HTR2CCYP19A1LMNA | |
| SCHEMBL29122626 | 0.76 | HTR2A (0.39) | HTR2CHTR2BOPRM1ADRA2AADRA2B | |
| SCHEMBL19490670 | 0.75 | SLC6A2 (0.43) | HTR2CHTR2BOPRM1ADRB2HTR1A | |
| SCHEMBL11931746 | 0.75 | HTR2C (0.38) | HTR2CHTR2BOPRM1ADRB2HTR1A | |
| SCHEMBL16060306 | 0.74 | LMNA (0.50) | HTR2CHTR2BOPRM1ADRB2HTR1A | |
| SCHEMBL226115 | 0.73 | LMNA (0.43) | HTR2CHTR1AHTR2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320651-B | Chiral amino-pyridine-phosphine tridentate ligand, manganese complex, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-01-17 | — | — | CN | disclosed |
| CN-111320651-A | Chiral amino-pyridine-phosphine tridentate ligand, manganese complex, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2020-06-23 | — | — | CN | disclosed |