SCHEMBL28416612

SCHEMBL28416612

NC(=O)N=S(=O)=O.NS(=O)(=O)c1ncc2nnnc-2[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL28246976 0.83
SCHEMBL6694889 0.71 CA1 (0.35)
SCHEMBL5597693 0.60 CA12 (0.32)
SCHEMBL34460358 0.59
SCHEMBL7754765 0.58
SCHEMBL27457813 0.58 ALDH1A1 (0.44)
SCHEMBL16454 0.58
SCHEMBL6692094 0.56 NPC1 (0.39)
Benzene SCHEMBL3120365 0.56 CYP3A4 (0.37)
SCHEMBL1571702 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102741267-B Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, methods of making, and uses thereof 帝斯曼知识产权资产有限公司 2020-06-23 CN disclosed