Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.34 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.34 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.34 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.34 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.34 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.34 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179249 | 0.97 | — | — | |
| Methane SCHEMBL27732895 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| SCHEMBL26111774 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Iodide SCHEMBL29201349 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Hydrochloric Acid SCHEMBL29201345 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Ethyl Chloride SCHEMBL28168736 | 0.86 | NFKB1 (0.41) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Bicarbonate SCHEMBL29201334 | 0.86 | TBXAS1 (0.51) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Acetic Acid SCHEMBL8525552 | 0.84 | TBXAS1 (0.50) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Bromide SCHEMBL28276997 | 0.80 | CYP11B1 (0.41) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| SCHEMBL22412682 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496486-A | Polyarylether material, polyarylether composite rubber sealing member and preparation method thereof | 西安航天动力研究所 | 2023-07-28 | — | — | CN | claimed |
| CN-113214524-B | Friction-resistant high-shear-resistant composite rubber sealing material | 四川大学 | 2022-06-07 | — | — | CN | claimed |
| CN-113416336-B | Fluorine-containing end group active hydroxyl friction-resistant high-shear-resistant composite rubber material | 四川大学 | 2022-06-07 | — | — | CN | claimed |
| CN-113416336-A | Fluorine-containing end group active hydroxyl friction-resistant high-shear-resistant composite rubber material | 四川大学 | 2021-09-21 | — | — | CN | claimed |
| CN-113214524-A | Friction-resistant high-shear-resistant composite rubber sealing material | 四川大学 | 2021-08-06 | — | — | CN | claimed |
| CN-111569676-B | Ultrafiltration membrane, nanofiltration membrane, preparation method thereof and ultrafiltration-nanofiltration reversible conversion method | 四川大学 | 2021-07-27 | — | — | CN | claimed |
| CN-111569680-B | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2021-03-19 | — | — | CN | claimed |
| CN-111569680-A | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2020-08-25 | — | — | CN | claimed |
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |
| CN-116496486-A | Polyarylether material, polyarylether composite rubber sealing member and preparation method thereof | 西安航天动力研究所 | 2023-07-28 | — | — | CN | disclosed |
| CN-111569676-B | Ultrafiltration membrane, nanofiltration membrane, preparation method thereof and ultrafiltration-nanofiltration reversible conversion method | 四川大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-111569680-B | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-111569676-A | Ultrafiltration membrane, nanofiltration membrane, preparation method thereof and ultrafiltration-nanofiltration reversible conversion method | 四川大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-111569680-A | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-110092907-B | Thioether-containing high-temperature-resistant shape memory polyamide resin and preparation method and application thereof | 四川大学 | 2020-05-26 | — | — | CN | disclosed |