Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179249 | 0.97 | — | — | |
| SCHEMBL26111774 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Bromide SCHEMBL28416620 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Methane SCHEMBL27732895 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Hydrochloric Acid SCHEMBL29201345 | 0.95 | NFKB1 (0.48) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Bicarbonate SCHEMBL29201334 | 0.86 | TBXAS1 (0.51) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Ethyl Chloride SCHEMBL28168736 | 0.86 | NFKB1 (0.41) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| Acetic Acid SCHEMBL8525552 | 0.84 | TBXAS1 (0.50) | NFKB1QPCTHSD17B10QPCTLCYP11B1 | |
| SCHEMBL22412682 | 0.79 | — | — | |
| SCHEMBL9783946 | 0.78 | CYP11B1 (0.49) | NFKB1CYP11B1CYP11B2CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813334-A | Onium salt, blocking agent dissociation catalyst for blocking isocyanate, blocked isocyanate composition containing blocking agent dissociation catalyst, thermosetting resin composition, cured product, and method for producing same | 广荣化学株式会社 | 2024-04-02 | — | — | CN | disclosed |