Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421991 | 0.89 | KMT2A (0.37) | L3MBTL1MEN1KMT2AHTTHDAC6 | |
| SCHEMBL28421990 | 0.81 | RXFP1 (0.46) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL28416663 | 0.81 | MEN1 (0.40) | L3MBTL1MEN1KMT2AHTTHDAC6 | |
| SCHEMBL28416681 | 0.80 | RXFP1 (0.43) | HTTLMNAMAPTTP53 | |
| SCHEMBL28419925 | 0.80 | SMN1; SMN2 (0.49) | L3MBTL1SMN1; SMN2MAPTTP53 | |
| SCHEMBL28796059 | 0.77 | KMT2A (0.41) | L3MBTL1MEN1KMT2AHTTHDAC6 | |
| SCHEMBL28426850 | 0.77 | ALDH1A1 (0.43) | L3MBTL1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL29889909 | 0.72 | MEN1 (0.46) | MEN1KMT2AHTTHDAC6SMN1; SMN2 | |
| SCHEMBL28427552 | 0.69 | TARBP2 (0.46) | L3MBTL1MEN1KMT2AHTTHDAC6 | |
| SCHEMBL28419614 | 0.67 | PIK3CD (0.40) | L3MBTL1MEN1KMT2AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981819-B | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110981819-A | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2020-04-10 | — | — | CN | disclosed |