Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423614 | 0.87 | ALOX12 (0.48) | TARBP2CYP19A1ALDH1A1POLBTDP1 | |
| SCHEMBL28422024 | 0.82 | MAPT (0.49) | TARBP2ALDH1A1POLBLMNAMAPT | |
| SCHEMBL28422077 | 0.80 | ALOX12 (0.64) | ALDH1A1POLBTDP1LMNAMAPT | |
| SCHEMBL29889909 | 0.79 | MEN1 (0.46) | ALDH1A1HTTMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28429182 | 0.78 | MAPT (0.67) | ALDH1A1POLBTDP1HTTLMNA | |
| SCHEMBL28421990 | 0.76 | RXFP1 (0.46) | ALDH1A1POLBHTTLMNAMAPT | |
| SCHEMBL28416681 | 0.75 | RXFP1 (0.43) | ALDH1A1HTTLMNAMAPT | |
| SCHEMBL11262770 | 0.75 | SMN1; SMN2 (0.40) | TARBP2ALDH1A1POLBLMNAMAPT | |
| SCHEMBL11254271 | 0.75 | SMN1; SMN2 (0.40) | TARBP2ALDH1A1POLBLMNAMAPT | |
| SCHEMBL11254260 | 0.74 | HSD17B10 (0.49) | TARBP2ALDH1A1POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981819-B | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110981819-A | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2020-04-10 | — | — | CN | disclosed |