Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416681 | 0.97 | RXFP1 (0.43) | RXFP1TP53HTTTSHRHPGD | |
| SCHEMBL28416663 | 0.89 | MEN1 (0.40) | TP53HTTCA2CA4MEN1 | |
| SCHEMBL28419925 | 0.85 | SMN1; SMN2 (0.49) | TP53HPGDCA2ALDH1A1MAPT | |
| SCHEMBL28796059 | 0.85 | KMT2A (0.41) | RXFP1TP53HTTMEN1KMT2A | |
| SCHEMBL28426850 | 0.83 | ALDH1A1 (0.43) | RXFP1TP53HTTCA2MEN1 | |
| SCHEMBL28416682 | 0.81 | L3MBTL1 (0.37) | TP53HTTMEN1KMT2AMAPT | |
| SCHEMBL28421991 | 0.78 | KMT2A (0.37) | TP53HTTMEN1KMT2AMAPT | |
| SCHEMBL28427552 | 0.76 | TARBP2 (0.46) | HTTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29889909 | 0.75 | MEN1 (0.46) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28945793 | 0.73 | KDM4E (0.44) | RXFP1TP53HTTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981819-A | Quinoxaline signal channel inhibitor and preparation method and application thereof | 广西师范大学 | 2020-04-10 | — | — | CN | disclosed |