Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325445 | 0.92 | PRSS1 (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16337241 | 0.87 | — | — | |
| SCHEMBL10481930 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL9487597 | 0.79 | ALDH1A1 (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8674490 | 0.79 | — | — | |
| Urethane SCHEMBL1054272 | 0.79 | ALOX15 (0.56) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10482090 | 0.78 | DGKA (0.44) | TSHRPRSS1PRSS2PRSS3 | |
| Urethane SCHEMBL28162966 | 0.77 | ALOX15 (0.54) | LMNACHRM2TSHRALOX15PRSS1 | |
| SCHEMBL28405434 | 0.77 | TSHR (0.45) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10481941 | 0.77 | TSHR (0.34) | TSHRPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660202-B | Water-soluble prodrugs | 大日本住友制药肿瘤公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-111295368-A | Chemically activated water soluble prodrugs | 大日本住友制药株式会社 | 2020-06-16 | — | — | CN | disclosed |