Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490221 | 0.78 | PTGS1 (0.59) | GAAKMT2ATRPV1POLBPTGS1 | |
| SCHEMBL29039314 | 0.78 | PTGS1 (0.59) | GAAKMT2ATRPV1POLBPTGS1 | |
| SCHEMBL26669264 | 0.77 | GAA (0.44) | GAAKMT2APOLBPTGS1NPC1 | |
| SCHEMBL28411875 | 0.75 | KMT2A (0.46) | GAAKMT2ATRPV1POLBPTGS1 | |
| SCHEMBL16702575 | 0.73 | GSK3A (0.57) | KMT2ATRPV1PTGS1SYKAURKA | |
| SCHEMBL29084255 | 0.72 | JAK2 (0.52) | KMT2APOLBSORT1SYKAURKA | |
| SCHEMBL5036428 | 0.71 | PTGS1 (0.66) | GAAKMT2ATRPV1POLBPTGS1 | |
| SCHEMBL3550940 | 0.70 | LMNA (0.54) | GAARPS6KB1NPC1RAB9ANNMT | |
| SCHEMBL30572236 | 0.70 | LMNA (0.54) | GAARPS6KB1NPC1RAB9ANNMT | |
| SCHEMBL3620154 | 0.70 | RAB9A (0.68) | GAAKMT2ATRPV1POLBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-A | Sulfonylpyridinylalkylamide substituted heteroaryl compounds | 百时美施贵宝公司 | 2020-06-19 | — | — | CN | claimed |
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-111315737-A | Sulfonylpyridinylalkylamide substituted heteroaryl compounds | 百时美施贵宝公司 | 2020-06-19 | — | — | CN | disclosed |