Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032545 | 1.00 | TSHR (0.38) | TSHRTHRBLMNADNM1SPHK1 | |
| SCHEMBL14690126 | 1.00 | TSHR (0.38) | TSHRTHRBLMNADNM1SPHK1 | |
| SCHEMBL27795146 | 1.00 | TSHR (0.38) | TSHRTHRBLMNADNM1SPHK1 | |
| SCHEMBL6705278 | 1.00 | TSHR (0.38) | TSHRTHRBLMNADNM1SPHK1 | |
| SCHEMBL6703622 | 0.98 | LMNA (0.34) | TSHRTHRBLMNATRPM8OPRM1 | |
| SCHEMBL704129 | 0.90 | — | — | |
| SCHEMBL2956129 | 0.90 | — | — | |
| SCHEMBL3235537 | 0.90 | — | — | |
| SCHEMBL3229740 | 0.90 | — | — | |
| SCHEMBL931336 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233916-A | Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof | 南京曙光精细化工有限公司 | 2020-06-05 | — | — | CN | disclosed |