SCHEMBL6705278

SCHEMBL6705278

CCCCCC[SiH2]OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.38
LMNA P02545 3/20 0.38
DNM1 Q05193 3/20 0.33
SPHK1 Q9NYA1 2/20 0.32
TRPM8 Q7Z2W7 4/20 0.32
OPRM1 P35372 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032545 1.00 TSHR (0.38) TSHRTHRBLMNADNM1SPHK1
SCHEMBL14690126 1.00 TSHR (0.38) TSHRTHRBLMNADNM1SPHK1
SCHEMBL27795146 1.00 TSHR (0.38) TSHRTHRBLMNADNM1SPHK1
SCHEMBL6703622 0.98 LMNA (0.34) TSHRTHRBLMNATRPM8OPRM1
SCHEMBL704129 0.90
SCHEMBL2956129 0.90
SCHEMBL3235537 0.90
SCHEMBL3229740 0.90
SCHEMBL931336 0.90
SCHEMBL703803 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080823-A Method for preparing tetramethylsilane and active siloxane by using low-boiling-point substances 郭兰 2024-12-06 CN disclosed
EP-4127078-A1 MICROBIAL REDUCTION COATING COMPOSITIONS AND METHODS OF USE THEREOF University of Houston System (US) 2023-02-08 EP disclosed
WO-2021195199-A1 MICROBIAL REDUCTION COATING COMPOSITIONS AND METHODS OF USE THEREOF UNIVERSITY OF HOUSTON SYSTEM (US) 2021-09-30 WO disclosed
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN disclosed
CN-101812304-A Liquid crystal aligning agent, liquid crystal display device and manufacture method thereof JSR CO LTD 2010-08-25 CN disclosed
CN-1536023-A Porous membrane shaping composition, preparation method of porous membrane, porous membrane intercalation insulating film and semiconductor device ��Խ��ѧ��ҵ��ʽ���� 2004-10-13 CN disclosed
US-20040076593-A1 Composition containing a modified nitrocellulose L'OREAL (FR) 2004-04-22 US disclosed
EP-1342731-A1 Cosmetic composition, especially nail enamel, comprising a modified nitrocellulose L'OREAL (FR) 2003-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040076593-A1 Composition containing a modified nitrocellulose VCL, C9, LPO TSHR 3730/4885THRB 3823/4885LMNA 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.