Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419045 | 0.89 | SMN1; SMN2 (0.45) | ARG1SMN1; SMN2TLR8ESR1ALDH1A1 | |
| SCHEMBL5082397 | 0.83 | ALDH1A1 (0.56) | ARG1SMN1; SMN2TLR8ALDH1A1POLB | |
| SCHEMBL5989122 | 0.82 | SMN1; SMN2 (0.40) | ARG1SMN1; SMN2ESR1ALDH1A1FLT1 | |
| SCHEMBL10448571 | 0.81 | TLR8 (0.56) | ARG1SMN1; SMN2TLR8ALDH1A1POLB | |
| SCHEMBL28420285 | 0.80 | SMN1; SMN2 (0.42) | ARG1SMN1; SMN2ESR1FLT1KDR | |
| SCHEMBL28285357 | 0.80 | TLR8 (0.54) | ARG1SMN1; SMN2TLR8ALDH1A1POLB | |
| Methane SCHEMBL28285372 | 0.80 | TLR8 (0.54) | ARG1SMN1; SMN2TLR8ALDH1A1POLB | |
| SCHEMBL10421136 | 0.80 | F13A1 (0.40) | ARG1SMN1; SMN2TLR8ESR1ALDH1A1 | |
| SCHEMBL28441745 | 0.80 | TLR8 (0.54) | ARG1SMN1; SMN2TLR8ALDH1A1POLB | |
| SCHEMBL28706114 | 0.79 | ALDH1A1 (0.39) | ARG1SMN1; SMN2TLR8ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-A | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-111187218-A | Application of 1-substituted-1H-imidazole-2-carboxylic acid compounds in preparation of metal β -lactamase inhibitor | 四川大学 | 2020-05-22 | — | — | CN | disclosed |