Methane

Methane

SCHEMBL28285372

C.CCCCCn1ccnc1C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.54
ALDH1A1 P00352 3/20 0.49
POLB P06746 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM5A P29375 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
KDM5B Q9UGL1 1/20 0.39
ARG1 P05089 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HTT P42858 1/20 0.38
AGTR1 P30556 1/20 0.38
AGTR2 P50052 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10448571 0.98 TLR8 (0.56) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL28441745 0.97 TLR8 (0.54) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL28285357 0.97 TLR8 (0.54) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL5082397 0.93 ALDH1A1 (0.56) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL28285396 0.86 SMN1; SMN2 (0.45) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL28034305 0.81 CYP1A2 (0.46) TLR8ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL28433183 0.80 TLR8 (0.50) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL28419650 0.80 ARG1 (0.44) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL28413273 0.79 SMN1; SMN2 (0.40) TLR8ALDH1A1POLBKMT2ACYP1A2
SCHEMBL300078 0.79 SMN1; SMN2 (0.47) ALDH1A1POLBKMT2ASMN1; SMN2ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563050-A Amide salt compound, for the catalyst of polyurethane production and the production method of polyurethane resin 广荣化学工业株式会社 2019-04-02 CN disclosed