Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448571 | 0.95 | TLR8 (0.56) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28285357 | 0.93 | TLR8 (0.54) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28441745 | 0.93 | TLR8 (0.54) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| Methane SCHEMBL28285372 | 0.93 | TLR8 (0.54) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28285396 | 0.89 | SMN1; SMN2 (0.45) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28419650 | 0.83 | ARG1 (0.44) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28413273 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL23497934 | 0.82 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28706114 | 0.82 | ALDH1A1 (0.39) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL300078 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1POLBKMT2ASMN1; SMN2ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165639-B | Wear-resistant lubricating oil coating material for mechanical bearing and preparation method thereof | 西安大力马能源科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118165639-A | Wear-resistant lubricating oil coating material for mechanical bearing and preparation method thereof | 西安大力马能源科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-3551632-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2019-10-16 | — | — | EP | disclosed |
| WO-2018108910-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2018-06-21 | — | — | WO | disclosed |
| US-20080051608-A1 | Preparation of alpha-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | DEGUSSA GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051608-A1 | Preparation of alpha-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | HACL2, PCCA, ECI1 | ALDH1A1 100/4885POLB 444/4885KMT2A 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.