Biphenyl

Biphenyl

SCHEMBL522299

OBO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
BCL2L1 Q07817 2/20 0.56
MMP3 P08254 1/20 0.56
MGLL Q99685 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HSD17B10 Q99714 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOTUM Q6P988 1/20 0.47
ALOX5 P09917 1/20 0.46
BACE1 P56817 1/20 0.45
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
WDR5 P61964 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4442099 1.00 ALDH1A1 (0.69) ALDH1A1BCL2L1MMP3MGLLCA1
SCHEMBL29156535 0.90 ALDH1A1 (0.56) ALDH1A1BCL2L1MMP3MGLLCA1
Biphenyl SCHEMBL28098924 0.88 ALDH1A1 (0.90) ALDH1A1BCL2L1MMP3MGLLCA1
SCHEMBL16597591 0.87 KMO (0.56) ALDH1A1BCL2L1MMP3MGLLHSD17B10
Biphenyl SCHEMBL1400373 0.85 HSD17B10 (0.65) ALDH1A1BCL2L1MMP3MGLLCA1
Biphenyl SCHEMBL28243758 0.84 ALDH1A1 (0.82) ALDH1A1BCL2L1MMP3MGLLCA1
Biphenyl SCHEMBL1358618 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3MGLLCA1
Biphenyl SCHEMBL164 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3MGLLCA1
SCHEMBL30108088 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3MGLLCA1
Biphenyl SCHEMBL4002609 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3MGLLCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113621215-B Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material 哈尔滨工业大学 2024-02-09 CN claimed
CN-113773503-B Boron-containing organic silicon tackifier and preparation method and application thereof 广东万木新材料科技有限公司 2022-08-19 CN claimed
CN-104788354-B A kind of synthetic method of 5- biphenyl-4-amino-2-methyl pentanoic acids intermediate 苏州苏旺森生物医药科技有限公司 2018-09-18 CN claimed
CN-104788354-A Synthesis method of 5-biphenyl-4-amino-2-methylvaleric acid intermediate SUZHOU TRIWIN PHARMACEUTICAL TECHNOLOGY CO LTD 2015-07-22 CN claimed
EP-2882793-A2 (PER)FLUOROPOLYETHERS WITH bi- OR ter-PHENYL END GROUPS Solvay Specialty Polymers Italy S.p.A. (IT) 2015-06-17 EP claimed
US-20150011446-A1 (PER)FLUOROPOLYETHERS WITH bi- OR ter-PHENYL END GROUPS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2015-01-08 US claimed
WO-2013120827-A2 (PER)FLUOROPOLYETHERS WITH bi- OR ter-PHENYL END GROUPS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2013-08-22 WO claimed
CN-119264347-A Degradable flame-retardant phenolic aerogel and preparation method and application thereof 中车成型科技(青岛)有限公司 2025-01-07 CN disclosed
CN-114835699-B Anthraofuran compound, intermediate, organic electroluminescent device and display device 阜阳欣奕华新材料科技股份有限公司 2024-11-05 CN disclosed
US-20240254150-A1 CONFORMATIONALLY RESTRICTED SULFONATE BASED PHOSPHINE LIGANDS FOR HINDERED SUZUKI COUPLING REACTIONS TCG GreenChem Inc. (US) 2024-08-01 US disclosed
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US disclosed
EP-4303218-A2 BENZO[B]NAPHTHO[2,3-D]FURANYL- OR BENZO[B]NAPHTHO[2,3-D]THIOPHENYL-TRIAZINE COMPOUNDS FOR ORGANIC ELECTRONIC ELEMENTS Duk San Neolux Co., Ltd. (KR) 2024-01-10 EP disclosed
CN-116323602-A High refractive index benzopyrrole derivative and organic electroluminescent element comprising same 株式会社乐普拓 2023-06-23 CN disclosed
WO-1997005163-A1 CYCLIC PEPTIDE ANTI-FUNGAL AGENTS ELI LILLY AND COMPANY (US) 1997-02-13 WO disclosed
EP-0757058-A1 Cyclic peptide anti-fungal agents ELI LILLY AND COMPANY (US) 1997-02-05 EP disclosed
WO-1996037512-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-11-28 WO disclosed
WO-1996037509-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-11-28 WO disclosed
EP-0744407-A2 Cyclic peptide antifungal agents ELI LILLY AND COMPANY (US) 1996-11-27 EP disclosed
EP-0744404-A2 Cyclic peptide antifungal agents ELI LILLY AND COMPANY (US) 1996-11-27 EP disclosed
WO-1995031461-A1 PREPARATION OF 2-ARYL CARBAPENEMS MERCK & CO., INC. (US) 1995-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254150-A1 CONFORMATIONALLY RESTRICTED SULFONATE BASED PHOSPHINE LIGANDS FOR HINDERED SUZUKI COUPLING REACTIONS STS, PTPRS, PFKFB1 ALDH1A1 1400/4885BCL2L1 2400/4885MMP3 4168/4885
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, NR2E3 ALDH1A1 242/4885BCL2L1 3029/4885MMP3 4861/4885
US-20150011446-A1 (PER)FLUOROPOLYETHERS WITH bi- OR ter-PHENYL END GROUPS PPARG, PARG, LIPC ALDH1A1 2652/4885BCL2L1 3265/4885MMP3 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.