SCHEMBL28420945

SCHEMBL28420945

C[Si](C)(CCC1CC2CCC1C2)O[Si](C)(C)O[Si](C)(C)CCC1CC2CCC1C2

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 6/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14848362 0.78 OPRK1 (0.35) OPRK1HPGDMEN1NPC1RAB9A
SCHEMBL16007717 0.77 LMNA (0.36) OPRK1HPGDMEN1NPC1RAB9A
SCHEMBL14770739 0.75 LMNA (0.36) OPRK1MEN1NPC1RAB9AKMT2A
SCHEMBL16007634 0.75 EPHX2 (0.33) OPRK1
SCHEMBL16007805 0.72 EPHX2 (0.33) OPRK1MEN1NPC1RAB9AKMT2A
SCHEMBL25233759 0.72 MEN1 (0.41) OPRK1HPGDMEN1NPC1RAB9A
SCHEMBL16007688 0.72 OPRK1 (0.35) OPRK1HPGDMEN1NPC1RAB9A
SCHEMBL13560019 0.72 OPRK1 (0.35) OPRK1HPGDMEN1NPC1RAB9A
SCHEMBL16007758 0.71 LMNA (0.34) OPRK1HPGDMEN1NPC1RAB9A
SCHEMBL16007865 0.69 LMNA (0.35) OPRK1MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111356759-A Stripper solution and method of using stripper solution 弗萨姆材料美国有限责任公司 2020-06-30 CN disclosed