Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | ARG2 | P78540 | 4/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 5/20 | 0.36 |
| ▸ | NOS2 | P35228 | 5/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27727355 | 0.88 | GSR (0.50) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL27808554 | 0.78 | GSR (0.57) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL30472848 | 0.78 | GSR (0.57) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL22533431 | 0.78 | GSR (0.71) | GSRDPP7DPP8DPP9ARG2 | |
| Bicarbonate SCHEMBL28058350 | 0.77 | — | — | |
| Lactic Acid SCHEMBL27658241 | 0.76 | TP53 (0.38) | DPP8DPP9 | |
| Lysine SCHEMBL20475717 | 0.76 | GSR (0.80) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL1484683 | 0.76 | GSR (0.80) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL7909339 | 0.76 | GSR (0.80) | GSRDPP7DPP8DPP9ARG2 | |
| Lysine SCHEMBL1484680 | 0.76 | GSR (0.80) | GSRDPP7DPP8DPP9ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110982054-B | Composite catalyst for catalytically synthesizing polycarbonate and method for catalytically synthesizing polycarbonate | 中国科学院过程工程研究所 | 2021-03-12 | — | — | CN | disclosed |
| CN-110982054-A | Composite catalyst for catalytically synthesizing polycarbonate and method for catalytically synthesizing polycarbonate | 中国科学院过程工程研究所 | 2020-04-10 | — | — | CN | disclosed |