Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419951 | 0.87 | SMN1; SMN2 (0.39) | CREBBPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28891091 | 0.86 | CREBBP (0.41) | CREBBPEP300MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28411099 | 0.86 | KDM4E (0.44) | CREBBPEP300ALDH1A1KMT2AMAPT | |
| SCHEMBL28410730 | 0.85 | CREBBP (0.40) | CREBBPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28418305 | 0.83 | CREBBP (0.43) | CREBBPEP300RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28417785 | 0.83 | CREBBP (0.44) | CREBBPEP300MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28416810 | 0.82 | ABCB1 (0.45) | CREBBPALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28881176 | 0.82 | CREBBP (0.56) | LCLAT1CREBBPBAZ2BMAPTTP53 | |
| SCHEMBL28415934 | 0.81 | CREBBP (0.40) | CREBBPEP300MEN1KMT2AMAPT | |
| SCHEMBL28415697 | 0.81 | CREBBP (0.58) | CREBBPEP300EPHB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320621-A | Indolizine compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2020-06-23 | — | — | CN | disclosed |