Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 5/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.58 |
| ▸ | PDE4A | P27815 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.51 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210131 | 0.90 | TNF (0.56) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL19210136 | 0.88 | TNF (0.53) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5424162 | 0.82 | TNF (1.00) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL6778554 | 0.82 | ADORA2B (0.62) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL17682312 | 0.81 | TNF (1.00) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL11302344 | 0.79 | ADORA2B (0.70) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL10018601 | 0.79 | TNF (0.71) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL6780041 | 0.79 | ADORA2B (0.65) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL27347024 | 0.78 | ADORA2B (0.65) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL6778295 | 0.78 | ADORA2B (0.65) | TNFADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-105566324-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-04-03 | — | — | CN | disclosed |