Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 5/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.60 |
| ▸ | PDE4A | P27815 | 2/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.52 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424162 | 0.83 | TNF (1.00) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL17682312 | 0.82 | TNF (1.00) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL8644270 | 0.80 | TNF (0.79) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL28422631 | 0.79 | TNF (0.69) | TNFADORA2BPDE4APDE4BPDE4C | |
| Bisdionin C SCHEMBL10018600 | 0.79 | CHIT1 (0.75) | TNFADORA2BPDE4APDE4BPDE4C | |
| Bisdionin D SCHEMBL16120988 | 0.79 | ADORA2B (0.79) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL516018 | 0.78 | PDE4A (0.78) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL8645950 | 0.78 | ADORA2B (0.63) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL8649006 | 0.78 | TNF (0.52) | TNFADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL16120981 | 0.78 | ADORA2B (0.77) | TNFADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207175-B2 | Inhibitor compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2012-06-26 | — | — | US | disclosed |
| US-20090215798-A1 | Inhibitor Compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215798-A1 | Inhibitor Compounds | ENGASE, MAN2B2, CHIA | TNF 4508/4885ADORA2B 4138/4885PDE4A 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.