Orthocresol

Orthocresol

SCHEMBL28422744

Cc1ccccc1O.OP(O)(=S)S

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 6/20 0.39
MAPT P10636 4/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 3/20 0.39
HPGD P15428 2/20 0.39
CA2 P00918 2/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 1/20 0.39
CA12 O43570 1/20 0.39
GMNN O75496 1/20 0.39
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL7651591 0.84 TRPA1 (0.43) TRPA1ATMCYP1A2CYP2C19ALDH1A1
Catechol SCHEMBL10692999 0.83 ALDH1A1 (0.59) CYP1A2CYP2C19ALDH1A1MAPTLMNA
SCHEMBL29102551 0.83 TRPA1 (0.71) TRPA1ATMCYP1A2CYP2C19ALDH1A1
Orthocresol SCHEMBL29395276 0.83
Orthocresol SCHEMBL8710164 0.83 TRPA1 (0.60) TRPA1ATMCYP1A2CYP2C19ALDH1A1
Orthocresol SCHEMBL170162 0.83 TRPA1 (0.60) TRPA1ATMCYP1A2CYP2C19ALDH1A1
Orthocresol SCHEMBL10419161 0.83 TRPA1 (0.60) TRPA1ATMCYP1A2CYP2C19ALDH1A1
Orthocresol SCHEMBL16002 0.83
Orthocresol SCHEMBL10534073 0.81 TRPA1 (0.48) TRPA1ATMCYP1A2CYP2C19ALDH1A1
Orthocresol SCHEMBL5498033 0.81 TRPA1 (0.48) TRPA1ATMCYP1A2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111403607-A Chelated perovskite material, film, device and preparation method and application thereof 华东理工大学 2020-07-10 CN disclosed