Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 9/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2970107 | 0.86 | ALDH1A1 (0.53) | FPR2LMNATNFCREBBPALDH1A1 | |
| SCHEMBL47378 | 0.83 | FPR2 (0.47) | FPR2LMNATNFCREBBPALDH1A1 | |
| SCHEMBL4230415 | 0.81 | FPR2 (0.46) | FPR2LMNATNFCREBBPALDH1A1 | |
| SCHEMBL21167189 | 0.81 | FPR2 (0.46) | FPR2LMNATNFCREBBPALDH1A1 | |
| SCHEMBL47376 | 0.81 | SMN1; SMN2 (0.65) | FPR2LMNATNFCREBBPALDH1A1 | |
| SCHEMBL4429718 | 0.79 | ESR1 (0.70) | FPR2TNFCREBBPALDH1A1ESR1 | |
| SCHEMBL17889253 | 0.79 | ESR1 (0.45) | FPR2LMNATNFESR1SMN1; SMN2 | |
| SCHEMBL18366017 | 0.77 | ALDH1A1 (0.58) | TNFALDH1A1SMN1; SMN2 | |
| SCHEMBL22356833 | 0.76 | FPR2 (0.43) | FPR2LMNATNFCREBBPALDH1A1 | |
| SCHEMBL17889248 | 0.76 | FPR2 (0.43) | FPR2LMNATNFCREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356680-B | Selective inhibitors of NLRP3 inflammasome | 诺瑟拉有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-111356680-A | Selective inhibitors of NLRP3inflammasome | 诺瑟拉有限公司 | 2020-06-30 | — | — | CN | disclosed |